Sept. 22, 2026 — Resident Evil opened to an estimated $108.3 million worldwide this weekend, marking the biggest launch in the franchise’s history, box office estimates show. At the same time, Zach Cregger’s Coyote Vs Acme is closing in on the $100 million global milestone after a steady theatrical run.
The $108.3 million figure represents the combined opening receipts across domestic and international markets. Early tallies put the new Resident Evil ahead of prior franchise entries for an opening weekend, giving the studio an immediate commercial victory out of the gate.
The result underscores the enduring appeal of established intellectual property in global theatrical markets. Resident Evil’s franchise track record and broad international distribution helped drive demand for the latest installment, even as release calendars remain crowded.
Coyote Vs Acme’s approach to $100 million illustrates a parallel box office pattern: titles built on recognizable brands can assemble substantial worldwide totals through steady legs and cross-demographic interest. The film’s continued accumulation suggests healthy word-of-mouth and sustained audience turnout beyond opening frames.
From a business perspective, a franchise-record opening strengthens the studio’s negotiating position for downstream revenue streams, including streaming windows, licensing and merchandising, and it improves the case for sequels or expanded franchise initiatives. Exhibitors and distributors will be watching weekday holds and regional performance closely to gauge long-term legs.
What to watch next: next weekend’s hold percentage for Resident Evil, whether Coyote Vs Acme crosses the $100 million threshold, and how upcoming releases affect both films’ trajectories. Final studio confirmations and audited grosses are pending, and this report will be updated as official numbers become available.
